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Showing results for "aboriginal respiratory"

Responsiveness of the human airway in vitro during deep inspiration and tidal oscillation

In healthy individuals, deep inspiration produces bronchodilation and reduced airway responsiveness, which may be a response of the airway wall to me…

Maternal and umbilical cord androgen concentrations do not predict digit ratio (2D:4D) in girls:

against developing autoimmune conditions and respiratory diseases. The research is now looking

Hospitalisations up to adulthood for children born with orofacial clefts

The aim of this study was to compare hospital admissions from infancy to adulthood, between children born with orofacial clefts (OFC) and those witho…

Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung d…

Responsiveness of the human airway in vitro during deep inspiration and tidal oscillation

The aim of this study was to examine the in vitro response of isolated human airways to the dynamic mechanical stretch associated with normal breathi…

Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma

Findings provide further proof of concept that pharmacological targeting of airway smooth muscle thickness will be beneficial and may be facilitated…

Changing Prevalence of Lower Airway Infections in Young Children with Cystic Fibrosis

Aspergillus species and P. aeruginosa are commonly present in the lower airways from infancy

Long-term medical and psychosocial outcomes in congenital diaphragmatic hernia survivors

Survivors of CDH may have significant adverse long-term medical and psychosocial issues that would be better recognised and managed in a multidiscipl…

Identification of epithelial phospholipase A2 receptor 1 as a potential target in asthma

PLA2R1 is increased in the airway epithelium in asthma, and serves as a regulator of airway hyperresponsiveness, airway permeability, antigen sensiti…

An observational study of febrile seizures: The importance of viral infection and immunization

Determine the frequency of detection of specific viral pathogens in children with febrile seizures