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Research

Streptococcus A is a bacterium often found in the throat and on the skin.

Research

Bullying is now regarded as a health problem and not just a disciplinary problem. Increasing evidence shows both traditional bullying (e.g. hitting, teasing) and cyberbullying have lasting effects on young people (both those who bully and those who are bullied), including damage to self-esteem, academic results and mental health.

Brain and behaviour research encompasses a child's learning, development and mental health - and the impact and development of conditions like cerebral palsy, autism and intellectual disability.

Interventions and explorations that focus on modifiable elements of the early life environment are being investigated, to assess and improve all aspects of physical and psychological wellbeing - both in childhood and in later life. These include nutrition, physical activity, time in nature, built environments, plastics and pollutants.

Research

Malaria remains a leading cause of illness and death globally, with countries in sub-Saharan Africa bearing a disproportionate burden. Global high-resolution maps of malaria prevalence, incidence, and mortality are crucial for tracking spatially heterogeneous progress against the disease and to inform strategic malaria control efforts. We present the latest such maps, the first since 2019, which cover the years 2000–22. The maps are accompanied by administrative-level summaries and include estimated COVID-19 pandemic-related impacts on malaria burden. 

ORIGINS has several sub-projects exploring allergy development within the cohort, with a focus on nutritional strategies for allergy prevention.

Research

Since its inception in 2005, the US President's Malaria Initiative (PMI) has played a major role in the reductions in malaria morbidity and mortality observed across Africa. With the status of PMI funding and operations currently uncertain, we aimed to quantify the impact that a fully functioning PMI would have on malaria cases and deaths in Africa during 2025. 

ORIGINS has sub-projects exploring the link between a mother's diet during pregnancy and health outcomes of the child. Projects also explore nutrition and eating habits during the early years.

As well as ORIGINS long-term core research, there are a number of clinical trials, early interventions and shorter-term research studies that sit within ORIGINS. Known as sub-projects, these studies look at multiple aspects of child and family health and development.

Research within this theme is exploring what it takes to help a child flourish and develop resilience as well as investigating long-term impacts on mental and physical health from childhood experience.