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Autistic-like traits in childhood predict later age at menarche in girls

We investigated the relationship between autistic-like traits in early childhood and age at menarche in typically developing girls.

Raine Foundation grants support exciting projects in childhood cancer and newborn infections

Two The Kids Research Institute Australia researchers have been awarded prestigious grants from the Raine Medical Research Foundation for projects in childhood cancer and newborn infection control.

STEPS - Equitable Approach to Early Self-Regulation Promotion

This research aims to co-design the components of a practical and equitable public health approach to promoting mental health in toddlers and young children in Western Australia (WA).

Validity and Reliability of the Early Development Instrument in Indonesia

This study finds that the EDI shows moderate validity and reliability in poor communities in Indonesia and highlights some of the difficulties associated with adapting western instruments for non-western cultures and contexts.

Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbations

Our findings suggest that the proportion of degranulated basophils can also be associated with recurrent exacerbations

Vitamin D over the first decade and susceptibility to childhood allergy and asthma

We aimed to research relationships between 25(OH)D levels from birth to 10 y/o and susceptibility to allergic sensitization, respiratory issues and asthma.

Joint developmental trajectories of internalizing and externalizing problems from mid-childhood to late adolescence and childhood risk factors: Findings from a prospective pre-birth cohort

There is limited evidence on heterogenous co-developmental trajectories of internalizing and externalizing problems from childhood to adolescence and predictors of these joint trajectories. We utilized longitudinal data from Raine Study participants to identify these joint trajectories from 5 to 17 years using parallel-process latent class growth analysis and analyze childhood individual and family risk factors predicting these joint trajectories using multinomial logistic regression.

A health inequality analysis of childhood asthma prevalence in urban Australia

Long-standing health inequalities in Australian society that were exposed by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic were described as "fault lines" in a recent call to action by a consortium of philanthropic organizations. With asthma a major contributor to childhood disease burden, studies of its spatial epidemiology can provide valuable insights into the emergence of health inequalities early in life.

Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy

Our data indicate epigenetic dysregulation in the early stages of signal transduction through the T cell receptor complex, and likely reflects pathways modified by gene-environment interactions in food allergy

The association between perinatal testosterone concentration and early vocabulary development

Prenatal exposure to testosterone is known to affect fetal brain maturation and later neurocognitive function.