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Research
The rare and undiagnosed diseases diagnostic service – application of massively parallel sequencing in a state-wide clinical serviceThe Rare and Undiagnosed Diseases Diagnostic Service refers to a genomic diagnostic platform operating within the Genetic Services of Western Australia
Comparing how mast cells are “programmed” in allergic and non-allergic children at one year of age.
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Neonatal drug withdrawal syndrome: Cross-country comparison using hospital administrative data in England, the USA, Western Australia and Ontario, Canada.We determined trends over time in the prevalence of neonatal drug withdrawal syndrome (NWS) in England compared with that reported in the USA, Western (W)...
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Interobserver reliability of the Australian Spasticity Assessment Scale (ASAS)The Australian Spasticity Assessment Scale complies with the definition of spasticity and is clinically feasible in paediatric settings
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Tightrope walking: Using predictors of 25 (OH)D concentration based on multivariable linear regression to infer associations with health risksThe approach of predicted 25 (OH)D concentration derived from multivariable linear regression may be valid..
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World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): PrebioticsDevelop evidence-based recommendations about the use of prebiotics in the prevention of allergy
Investigating the physical impact of Long COVID on ORIGINS families
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Functional annotation of the vlinc class of non-coding RNAs using systems biology approachWe show that vlincRNAs genes likely function in cis to activate nearby genes
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A randomized controlled trial of the effects of n-3 fatty acids on resolvins in chronic kidney diseaseSpecialized Proresolving Lipid Mediators are increased after 8 weeks n-3 fatty acid supplementation in patients with chronic kidney disease
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Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczemaElevated egg-specific Th2 cytokine responses were established prior to egg ingestion at 4months and were not significantly altered by introduction of egg
Antibiotic dysbiosis and probiotics trial on infants
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The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitisThese findings also suggest that variants in ERAP1 have a differential impact on the risk of AAU when compared with AS, and hence the genetic risk for AAU...
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Predominant bacteria detected from the middle ear fluid of children experiencing otitis media: A systematic reviewGlobally, S. pneumoniae and H. influenzae remain the predominant otopathogens associated with OM as identified through bacterial culture
This study is investigating whether a machine learning based approach can be used to improve fetal brain anatomy measurement for learning development studies.
This study explores the role of infant sleep in early childhood development.
The BioMood project will study how following a Mediterranean diet during pregnancy affects the gut microbiome, metabolism, and inflammation, with the expectation that it will promote a healthier microbiome and better mental health.
Does the amount of eggs and peanuts a mother eats during pregnancy and breastfeeding have an influence on whether her baby will develop an egg or peanut food allergy?
This sub-project aims to fill the gap in knowledge of the effects of climate change on child health and wellbeing in Australia, and to propose data-driven adaptation trials to counter the most serious impacts.