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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained

Understanding group A streptococcal pharyngitis and skin infections as causes of rheumatic fever: Protocol for a prospective disease incidence study

This study will identify the incidence of true Group A Streptococcal pharyngitis and serological responses to Group A Streptococcal GAS skin infections

A large proportion of poor birth outcomes among Aboriginal Western Australians are attributable to smoking, alcohol and substance misuse, and assault

A large proportion of adverse outcomes were attributable to the modifiable risk factors of substance use and assault

Powered standing wheelchairs promote independence, health and community involvement in adolescents with Duchenne muscular dystrophy

This study used qualitative methods to explore how adolescents with Duchenne muscular dystrophy used a powered wheelchair standing device in their daily lives

Association between psychotic experiences and non-accidental self-injury: results from a nationally representative survey of adolescents

Adolescents reporting any sychotic experiences in the past 12 months reported increased likelihood of non-accidental self-injury in the same time period

Features of the metabolic syndrome in late adolescence are associated with impaired testicular function at 20 years of age

Adolescents with features of metabolic disorder or insulin resistance show impaired testicular function and altered hormone levels

Associations between the home yard and preschoolers’ outdoor play and physical activity

Features of the home-yard physical environment were positively associated with preschoolers’ outdoor play and physical activity

Apgar score and risk of autism

This study suggests that low Apgar score is associated with higher risk of autism spectrum disorder, and in particular autistic disorder

Clinical Ecology-Transforming 21st-Century Medicine with Planetary Health in Mind

The grand, interconnected challenges of our time demands that all of medicine be viewed from an ecological perspective

Maternal pre-pregnancy weight and autistic-like traits among offspring in the general population

This study provides further evidence that maternal pre-pregnancy obesity is associated with autism-like behaviors in offspring