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Cancer incidence in the Western Australian mining industryWorking underground emerged as a significant determinant of lung cancer risk in our contemporary mining cohort
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Infant feeding and growth trajectory patterns in childhood and body composition in young adulthoodFull breastfeeding for <3 months compared with ≥3 months may be associated with rapid growth in early childhood and body composition in young adulthood
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Clonal expansion of new penicillin-resistant clade of neisseria meningitidis serogroup w clonal complex 11, AustraliaIn Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016
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Burkholderia pseudomallei evades Nramp1 (Slc11a1)- and NADPH oxidase-mediated killing in macrophages and exhibits Nramp1-dependent virulence gene expressionHere we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1+) control the net replication of B. thailandensis, but not B. pseudomallei.
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PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivoOur results reveal long-lasting changes to progenitor cells of monocytes/macrophages by a 2-hour dimethyl PGE2 pulse that, in turn, limits the migration of their daughter cells to chemoattractants and inflammatory mediators.
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Relationship between out-of-home care placement history characteristics and educational achievement: A population level linked data study.This study examined the influence of placement stability, reunification, type of care, time in care and age at entry to care on children's educational outcomes.
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Poverty and child behavioral problems: The mediating role of parenting and parental well-beingThe results show that certain parenting styles, such as psychological control, as well as mothers’ life satisfaction partially mediate the correlation between poverty and child behavioral problems.
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Is cellular heterogeneity merely a confounder to be removed from epigenome-wide association studies?DNA methylation is a very sensitive measure of cell fate mix and therefore reveals much about underlying disease etiology including aspects of causation.
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Maternal Alcohol Use Disorder and Risk of Child Contact with the Justice System in Western Australia: A Population Cohort Record Linkage StudyChildren who were exposed to a maternal alcohol use disorder had significantly increased odds of contact with the justice system.
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Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrityIn disease settings, vitamin D may be important for maintaining optimal lung epithelial integrity and suppressing inflammation, but less is known of its effects prior to disease onset.