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Revisiting the inoculum effect for Streptococcus pyogenes with a hollow fibre infection model

Severe, invasive Streptococcus pyogenes (Strep A) infections result in greater than 500,000 deaths annually. First line treatment for such infections is benzylpenicillin, often with the addition of clindamycin, but treatment failure can occur with this regimen. This failure has been partially attributed to the inoculum effect, which presents as reduced antibiotic susceptibility during high bacterial density and plateau-phase growth.

Congenital anomalies in children with postneonatally acquired cerebral palsy: an international data linkage study

To describe the major congenital anomalies present in children with postneonatally acquired cerebral palsy (CP), and to compare clinical outcomes and cause of postneonatally acquired CP between children with and without anomalies.

Maternal diet, depression and antidepressant treatment in pregnancy and across the first 12 months postpartum in the MPEWS pregnancy cohort study

There is increasing interest in the association between perinatal depression and diet including whether diet may have an impact on depressive symptoms and equally whether depression influences diet. Furthermore, whether pharmacological treatment of depression with antidepressant medication also may influence diet.

The Development and Feasibility of a Manualised Therapeutic Playgroup for Children with Developmental Delay

Playgroups are widely used throughout the Australian community yet understanding of their efficacy is hindered by inconsistent playgroup definitions and practice principles. This study aimed to develop, implement and evaluate the feasibility of a manualised therapeutic playgroup for children with developmental delay and their families using a three step process.

Telehealth for Diagnosis of Hearing Loss

Telehealth offers unique opportunities for providing access to hearing healthcare ser- vices to underserved populations

Making visible the invisible: Aboriginal forensic mental health

The health of Aboriginal and Torres Strait Islander people in Australia is crucial to address due to the burden of disease and injury in aboriginal population.

Female Empowerment as a Core Driver of Democratic Development: A Dynamic Panel Model from 1980 to 2005

Investigated the causal effects of female empowerment on democratic development for 97 countries from 1980 to 2005.

Validation of a model for optimal birth weight: A prospective study using serial ultrasounds

The aim of this study was to validate a model for optimal birth weight derived from neonatal records, and to test the assumption that preterm births may be...

Epidemiology of the cerebral palsies

Half of the most severe cases of cerebral palsy (CP) survive to adulthood, but because this longevity is relatively recent, there is no empirical experience of

Dietary glycaemic carbohydrate in relation to the metabolic syndrome in adolescents:

High dietary glycaemic carbohydrate, as measured by the dietary glycaemic index and glycaemic load has been associated with increased risk of the metabolic synd