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Hereditary cancer predisposition syndromes (HCPS) account for at least 10% of paediatric cancers.1 Li‐Fraumeni syndrome (LFS) is a dominant HCPS caused by mutations in the TP53 gene and is associated with an 80–90% lifetime risk of cancer, commencing in infancy.2 Children of affected individuals are at 50% risk of inheriting the family mutation.
The 2001 Recommendations for clinical care guidelines on the management of otitis media in Aboriginal and Torres Islander populations were revised in 2010. This 2020 update by the Centre of Research Excellence in Ear and Hearing Health of Aboriginal and Torres Strait Islander Children used for the first time the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.
Study the innate immune function in ulcerative colitis patients who fail to respond to anti-tumor necrosis factor therapy
Positive impact of peer-led home visiting parent support programs, incorporating a framework of partnership between parents and home visitors
This trial will determine the effectiveness of the TOBY App as a therapeutic complement to other early interventions children with ASD receive
The prevalence of mental disorders in children and adolescents in Australia, and the severity and impact of those mental disorders
Aims, sample design, development of survey content, field procedures and final questionnaires of the Young Minds Matter study
After brief training, health workers with no prior experience in echocardiography can obtain adequate quality images and make a reliable assessment
There are links between problem behaviours associated with Internet use and electronic gaming, and mental disorders and risk-taking behaviour in young people
The PneuCarriage project, a large, international multi-centre study for the identification of the best pneumococcal serotyping methods for carriage studies