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Patient-reported outcome measures for paediatric acute lower respiratory infection studiesPatient-reported outcome measures (PROMs) are recommended for capturing meaningful outcomes in clinical trials. The use of PROMs for children with acute lower respiratory infections (ALRIs) has not been systematically reported. We aimed to identify and characterise patient-reported outcomes and PROMs used in paediatric ALRI studies and summarise their measurement properties.
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A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancerMolecular profiling of the tumour immune microenvironment (TIME) has enabled the rational choice of immunotherapies in some adult cancers. In contrast, the TIME of paediatric cancers is relatively unexplored. We speculated that a more refined appreciation of the TIME in childhood cancers, rather than a reliance on commonly used biomarkers such as tumour mutation burden (TMB), neoantigen load and PD-L1 expression, is an essential prerequisite for improved immunotherapies in childhood solid cancers.
 
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Top five things you should know about the measlesDr Tom Snelling from The Kids explains the top five things you should know about the virus and why having the measles vaccine is so important.
 
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Consumer Representative SpotlightMeet Rachelle Ward one of our Consumer Representatives
 
     
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JDRF one talk with Prof Liz DavisJDRF ONE TALK WITH... PROFESSOR LIZ DAVIS Tune into JDRF Australia instagram page Wednesday 20 October from 3PM WST to hear our Co-Director Professor Liz Davis chat about the diabetes research she's involved in and why she does it. JDRF Australia (@jdrfaus) • Instagram photos and videos
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Onset of maternal psychiatric disorders after the birth of a child with autism spectrum disorder: A retrospective cohort studyMothers of a child with autism spectrum disorder have more psychiatric disorders after the birth of their child.
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Influenza C infections in Western Australia and Victoria from 2008 to 2014Comparison of Influenza C viruses detected from Australian clinical samples with Influenza C viruses detected in other parts of the world in recent years
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Optimise+Optimise+ is a research project designed to build on the best parts of LGBTQ+ community-controlled mental health and AOD services across Australia, with the aim of further enhancing service options.
Research
Establishing the lowest penicillin concentration to prevent pharyngitis due to Streptococcus pyogenes using a human challenge model (CHIPS)The in-vivo plasma concentration of penicillin needed to prevent Streptococcus pyogenes pharyngitis, recurrent acute rheumatic fever, and progressive rheumatic heart disease is not known. We used a human challenge model to assess the minimum penicillin concentration required to prevent streptococcal pharyngitis.