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Research

Patient-reported outcome measures for paediatric acute lower respiratory infection studies

Patient-reported outcome measures (PROMs) are recommended for capturing meaningful outcomes in clinical trials. The use of PROMs for children with acute lower respiratory infections (ALRIs) has not been systematically reported. We aimed to identify and characterise patient-reported outcomes and PROMs used in paediatric ALRI studies and summarise their measurement properties.

Research

A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

Molecular profiling of the tumour immune microenvironment (TIME) has enabled the rational choice of immunotherapies in some adult cancers. In contrast, the TIME of paediatric cancers is relatively unexplored. We speculated that a more refined appreciation of the TIME in childhood cancers, rather than a reliance on commonly used biomarkers such as tumour mutation burden (TMB), neoantigen load and PD-L1 expression, is an essential prerequisite for improved immunotherapies in childhood solid cancers.

News & Events

Top five things you should know about the measles

Dr Tom Snelling from The Kids explains the top five things you should know about the virus and why having the measles vaccine is so important.

News & Events

Consumer Representative Spotlight

Meet Rachelle Ward one of our Consumer Representatives

News & Events

JDRF one talk with Prof Liz Davis

JDRF ONE TALK WITH... PROFESSOR LIZ DAVIS  Tune into JDRF Australia instagram page Wednesday 20 October from 3PM WST to hear our Co-Director Professor Liz Davis chat about the diabetes research she's involved in and why she does it. JDRF Australia (@jdrfaus) • Instagram photos and videos

Research

Onset of maternal psychiatric disorders after the birth of a child with autism spectrum disorder: A retrospective cohort study

Mothers of a child with autism spectrum disorder have more psychiatric disorders after the birth of their child.

Research

Influenza C infections in Western Australia and Victoria from 2008 to 2014

Comparison of Influenza C viruses detected from Australian clinical samples with Influenza C viruses detected in other parts of the world in recent years

Research

Optimise+

Optimise+ is a research project designed to build on the best parts of LGBTQ+ community-controlled mental health and AOD services across Australia, with the aim of further enhancing service options.

Research

Establishing the lowest penicillin concentration to prevent pharyngitis due to Streptococcus pyogenes using a human challenge model (CHIPS)

The in-vivo plasma concentration of penicillin needed to prevent Streptococcus pyogenes pharyngitis, recurrent acute rheumatic fever, and progressive rheumatic heart disease is not known. We used a human challenge model to assess the minimum penicillin concentration required to prevent streptococcal pharyngitis.