Skip to content

Search

Showing results for "clinical trials"

Western Australian emergency department presentations related to child maltreatment and intentional injury

To determine the proportion of child maltreatment-related emergency department presentations in WA and describe the types of injuries associated with them.

Pharmacokinetics of intramuscular versus subcutaneous administration of Benzathine Penicillin G

Benzathine penicillin G (BPG) has been in use since the 1950s for treatment of skin infections, bacterial pharyngitis, syphilis and prevention of recurrent episodes of acute rheumatic fever (ARF)

Publications

Browse the published work of the Centre's researchers

The right interventions for each child with cerebral palsy

This paper is a comment on an article published in a previous edition of the journal on a clinical intervention strategy for children with cerebral palsy.

Suicide by young Australians, 2006-2015: a cross-sectional analysis of national coronial data

Objective: To assess the demographic, social, and clinical characteristics of young Australians who die by suicide.

Study of pediatric appendicitis scores and management strategies: A prospective observational feasibility study

The objective was to investigate the feasibility of prospectively validating multiple clinical prediction scores for pediatric appendicitis in an Australian pediatric emergency department. 

Contact us

CliniKids has two clinics - in Subiaco and also in Joondalup.

Public Health Approach to Child Abuse and Neglect: Antecedents and Outcomes

Melissa Fiona Helen Rebecca Peter O'Donnell Stanley Leonard Glauert Jacoby BPsych (Hons), MPsych, GradDip Ed, PhD FAA FASSA MSc MD FFPHM FAFPHM FRACP

Subcutaneous infusion of high-dose benzathine penicillin G is safe, tolerable, and suitable for less-frequent dosing for rheumatic heart disease secondary prophylaxis: a phase 1 open-label population pharmacokinetic study

Since 1955, the recommended strategy for rheumatic heart disease secondary prophylaxis has been benzathine penicillin G injections administered intramuscularly every 4 weeks. Due to dosing frequency, pain, and programmatic challenges, adherence is suboptimal. It has previously been demonstrated that BPG delivered subcutaneously at a standard dose is safe and tolerable and has favorable pharmacokinetics, setting the scene for improved regimens with less frequent administration.

Developing and characterising juvenile models of aggressive paediatric brain cancers for the evaluation of novel immunotherapies.

While profound treatment responses have been realised using immunotherapy for some cancer types, this is yet to be seen for paediatric brain cancer patients.