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Showing results for "early lung health"

DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

DNA methylation has been shown to be associated with adiposity in adulthood. However, whether similar DNA methylation patterns are associated with childhood and adolescent body mass index (BMI) is largely unknown. More insight into this relationship at younger ages may have implications for future prevention of obesity and its related traits. We examined whether DNA methylation in cord blood and whole blood in childhood and adolescence was associated with BMI in the age range from 2 to 18 years using both cross-sectional and longitudinal models.

Differential DNA methylation of steatosis and non-alcoholic fatty liver disease in adolescence

Epigenetic modifications are associated with hepatic fat accumulation and non-alcoholic fatty liver disease (NAFLD). However, few epigenetic modifications directly implicated in such processes have been identified during adolescence, a critical developmental window where physiological changes could influence future disease trajectory. To investigate the association between DNA methylation and NAFLD in adolescence, we undertook discovery and validation of novel methylation marks, alongside replication of previously reported marks.

Characterising symptomatic substates in individuals on the psychosis continuum: a hidden Markov modelling approach

To improve early intervention and personalise treatment for individuals early on the psychosis continuum, a greater understanding of symptom dynamics is required. We address this by identifying and evaluating the movement between empirically derived attenuated psychotic symptomatic substates-clusters of symptoms that occur within individuals over time.

Natural environments, nature relatedness and the ecological theater: connecting satellites and sequencing to shinrin-yoku

Mechanisms-including aerobiological and epigenetic-that might help explain some of the noted positive health outcomes

Discover Day

Join us this school holidays for a FREE family fun day at The Kids Research Institute Australia in Subiaco and discover how we are making a difference to child health.

Dr Ruth Thornton

Co-head, Bacterial Respiratory Infectious Disease Group (BRIDG)

A BRIGHT day for little lungs

Families affected by bronchiectasis gathered in Kings Park recently for a special event hosted by the BRIGHT Study team, celebrating community, connections, and conversations.

Evaluation of the Community Playgroup Program

This evaluation explored the facilitators & barriers that influence Community Playgroup attendance, and the impact of attending playgroups on child development.

The oral and written narrative language skills of adolescent students in youth detention and the impact of language disorder

Unmet language and literacy needs are common among young people who are involved with youth justice systems. However, there is limited research regarding the functional text-level language skills of this population with regard to narrative macrostructure (story grammar) and microstructure (semantics and syntax) elements. In this study, we examined macrostructure and microstructure elements in the oral and written narrative texts of 24 adolescent students of a youth detention centre. The students, who were aged 14- to 17- years, were all speakers of Standard Australian English, and 11 (46%) students met criteria for language disorder (LD).

Colostrum, the missing link for healthy growth

Valerie Verhasselt MD, PhD Head, Immunology and Breastfeeding 0402997617 Valerie.verhasselt@thekids.org.au Head, Immunology and Breastfeeding @