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Showing results for "clinical trials"

Six Months of Hybrid Closed-Loop Versus Manual Insulin Delivery With Fingerprick Blood Glucose Monitoring in Adults With Type 1 Diabetes: A Randomized, Controlled Trial

To investigate glycemic and psychosocial outcomes with hybrid closed-loop (HCL) versus user-determined insulin dosing with multiple daily injections (MDI) or insulin pump (i.e., standard therapy for most adults with type 1 diabetes). Adults with type 1 diabetes using MDI or insulin pump without continuous glucose monitoring (CGM) were randomized to 26 weeks of HCL (Medtronic 670G) or continuation of current therapy.

Use of Continuous Glucose Monitoring Trends to Facilitate Exercise in Children with Type 1 Diabetes

This study investigated the use of a carbohydrate intake algorithm based on continuous glucose monitoring trends during physical activity

Cardiac autonomic dysfunction is associated with high-risk albumin-to-creatinine ratio in young adolescents with type 1 diabetes in AdDIT

This study examined the association between cardiac autonomic dysfunction and high albumin-to-creatinine ratio (ACR) in adolescents with type 1 diabetes.

Acute hyperglycaemia does not alter nitric oxide-mediated microvascular function in the skin of adolescents with type 1 diabetes

Impact of an acute bout of hyperglycaemia on nitric oxide (NO)-mediated microvascular function in the skin of adolescents with type 1 diabetes

Papers & Publications

Publications, papers and findings coming out of ORIGINS and its sub-projects

All through the night

For the parent of a child living with diabetes, sleep no longer represents the relaxing slumber that it used to.

Neural tube defects in Australia and food fortification with folic acid

Promotion of periconceptional folic acid supplement use began in Australia following publication of randomised trials showing effectiveness.

Fortification of flour with folic acid

After randomized, controlled trials established that consumption of folic acid before pregnancy and during the early weeks of gestation reduces the risk...

Clustering of Wellbeing, Engagement and Academic Outcomes in Australian Primary Schools

The mental health and wellbeing of young people has important consequences for students and society. Schools are a logical environment for management and early intervention of wellbeing, mental health and engagement with school. Interventions aimed at improving mental health and wellbeing in education systems requires knowledge of how wellbeing is clustered at a school level. Cluster-randomised trials, and regression analyses of such data also require knowledge of clustering.

New vaccine promises fewer needles

Perth researchers are calling for help from Perth toddlers and their parents to participate in a new project that aims to reduce the number of injections