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Ruth Elke Peter Thornton Seppanen Richmond PhD BSc PhD MBBS MRCP(UK) FRACP Co-head, Bacterial Respiratory Infectious Disease Group (BRIDG) Program
Otitis media (OM) starts within weeks of birth in almost all Indigenous infants living in remote areas of the Northern Territory (NT).
Otitis media (OM) is a common disease in early childhood characterised by inflammation of the middle ear.
This study was the first to concurrently identify middle ear pathogens in both bacterial biofilm and intracellularly in the middle ear mucosa of children and to identify extensive DNA stranding in the MEF from children with AOM
We identified several novel candidate genes which warrant further analysis in cohorts matched more precisely for clinical phenotypes.
Both bacteria and viruses play a role in the development of acute otitis media, however, the importance of specific viruses is unclear.
We investigated predictors of nasopharyngeal carriage in Australian Aboriginal and non-Aboriginal children.
Otitis media (OM) is among the most common illnesses of early childhood, characterised by the presence of inflammation in the middle ear cavity...
Otitis media is very common in Aboriginal children in Western Australia and chronic ear disease causes major problems in speech and language development and education. Up until recently, most programmes dealing with the problem of OM have focused on clinical interventions rather than prevention. The Enhanced Prevention Working Group was established as part of the WA Child Ear Health Strategy (2017–2021). The Group has worked collaboratively to develop a set of recommendations for prevention of OM in Aboriginal children.
We have demonstrated that a single dose of a closely related commensal can delay onset of NTHi otitis media in vivo