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Showing results for "early childhood"

Pubertal trajectory in females with Rett syndrome: A population-based study

The aim of this study was to describe pubertal development in a population-based cohort of females with Rett syndrome.

Novel end points for clinical trials in young children with cystic fibrosis

Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality.

Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study

The objective of this study was to compare international trends in pre-eclampsia rates and in overall pregnancy hypertension rates...

The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine model

Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with vascular-based disorders.

Maternal Pre-pregnancy Body Mass Index and Offspring Temperament and Behavior at 1 and 2 Years of Age

Recent research suggests that fetal exposure to increased maternal body mass index (BMI) during pregnancy may be associated with psychopathology later in life.

Factors influencing the assessment of lung function in mice with influenza-induced lung disease

The constant-phase model (CPM) is commonly fit to respiratory system input impedance (Z rs) to estimate lung mechanics.

Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study

Increased prenatal testosterone exposure has been hypothesized as a mechanism underlying autism spectrum disorders (ASD).

TLR3 and RIG-I gene variants: Associations with functional effects on receptor expression and responses to measles viru

Measles virus causes severe morbidity and mortality, despite the availability of measles vaccines. Successful defence against viral pathogens requires early...

Maternal Pre-pregnancy Body Mass Index and Offspring Temperament and Behavior at 1 and 2 Years of Age

Recent research suggests that fetal exposure to increased maternal body mass index (BMI) during pregnancy may be associated with psychopathology later in life.

Assessing Clinical Deterioration in Children With Dark-Coloured Skin: A Scoping Review

Background: Signs of clinical deterioration may appear differently in children with dark-coloured skin. How to assess children in this cohort is currently poorly defined. Aim: To explore available information on the assessment of clinical deterioration in children with dark-coloured skin and identify research deficits.