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Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells

This study assessed an alternative approach, using a small scale halide assay that can be adapted for a personalized high throughput setting to analyze CFTR function of pAEC.

Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung

We aimed to delineate the effects of LPS and AMP on airway inflammation, and potential contribution to airway disease by measuring airway inflammatory responses

UV Irradiation of Skin Enhances Glycolytic Flux and Reduces Migration Capabilities in Bone Marrow–Differentiated Dendritic Cells

A systemic immunosuppression follows UV irradiation of the skin of humans and mice.

The bioenergetics of inflammation: insights into obesity and type 2 diabetes

Diabetes mellitus is one of the most common chronic metabolic disorders worldwide, and its incidence in Asian countries is alarmingly high.

An exposome perspective: Early-life events and immune development in a changing world

Here we review the historical origins of exposome research and define a new concept, the metaexposome

Evolving Identification of Blood Cells Associated with Clinically Isolated Syndrome: Importance of Time since Clinical Presentation and Diagnostic MRI

This study aimed to identify a CIS peripheral blood signature that may provide clues for potential immunomodulatory approaches early in disease

Molecular actions of Vitamin D in reproductive cell biology

The aim of this work is to review current metabolic and molecular aspects of the VitD-VitD receptor axis in reproductive medicine

House Dust Mite Allergens: New Discoveries and Relevance to the Allergic Patient

Recent findings on house dust allergens and their contribution to knowledge that will significantly impact current and future allergy treatments are appraised

Timing of routine infant vaccinations and risk of food allergy and eczema at one year of age

There was no overall association between delayed DTaP and food allergy; however, children with delayed DTaP had less eczema and less use of eczema medication

Hospitalisations up to adulthood for children born with orofacial clefts

The aim of this study was to compare hospital admissions from infancy to adulthood, between children born with orofacial clefts (OFC) and those without OFC.