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An update on allergy and anaphylaxis in pediatric anesthesia

We review the pathophysiology of hypersensitivity reactions and the implications for anesthesia of food allergy, atopy, and family history of allergy in children

Multiomics and Systems Biology Are Needed to Unravel the Complex Origins of Chronic Disease

In this concept paper, we discuss multiomic approaches to studying immune dysregulation and highlight some of the challenges and opportunities

Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation

These data provide proof of concept supporting the rationale for developing transplacental immune reprogramming approaches for primary disease prevention

Reduced heart rate variability in remitted bipolar disorder and recurrent depression

Heart Rate Variability was found to be lower in the bipolar and depression groups, compared with control subjects

Rhinovirus-induced asthma exacerbations and risk populations

Asthma exacerbations are heterogeneous conditions that involve the complex interplay between environmental exposures and innate and adaptive immune function

The negotiations of involved fathers and intensive mothers around shared-bed sleeping with infants (co-sleeping

This article discusses some emerging issues that arose during a much wider evaluative investigation of the Western Australian Health Department's bed-sharing...

MS in South Asians in England: Early disease onset and novel pattern of myelin autoimmunity

Epidemiological studies describe a latitude gradient for increased MS prevalence and a preponderance of disease in Caucasian individuals.

Lung function, airway inflammation, and polycyclic aromatic hydrocarbons exposure in mexican schoolchildren: A pilot study

To determine the association of exposure to polycyclic aromatic hydrocarbons (PAHs) with lung function and pH of exhaled breath condensate (EBC) in Mexican...

Grey matter changes associated with deficit awareness in mild cognitive impairment: A voxel-based morphometry study

We examined the association of insight and grey matter volume using a voxel-based morphometry approach in volunteers with and without mild cognitive impairment.

Immunotherapy drug dramatically improves survival for babies with rare leukaemia

A pilot clinical study, led in Australia by a The Kids Research Institute Australia and Perth Children's Hospital researcher, has found an immunotherapy drug can dramatically increase survival rates for babies with a rare form of leukaemia, paving the way for a major international clinical trial.