Search
Showing results for "early lung health"
Research
The effects of in utero vitamin D deficiency on airway smooth muscle mass and lung functionIn this study, we aimed to uncover the molecular mechanisms contributing to altered lung structure and function.
Research
Kids Easy Breathing StudyAs both bronchiolitis and bronchiectasis are diseases of the airway surface, we will comprehensively study the airway surface and factors affecting the airway surface in infants hospitalised with bronchiolitis.
Research
Premedication with salbutamol prior to surgery does not decrease the risk of perioperative respiratory adverse events in school-aged childrenPremedication with salbutamol to children prior to their surgery did not reduce their risk of Perioperative respiratory adverse events
Research
Sexual dimorphism in lung function responses to acute influenza A infectionMales are generally more susceptible to respiratory infections; however, there are few data on the physiological responses to such infections in males and...
Research
Exposomes and metabolic health through a physical activity lens: a narrative reviewIn this narrative review, we provide an overview of the role of physical activity as part of differing exposomes (our combined non-genetic exposures from conception onwards) and environmental influences on metabolic health. We discuss 'beneficial' exposomes (green/natural outdoor spaces, sun exposure, healthy diets and features of built environments) that could synergise with physical activity to prevent metabolic dysfunction, particularly that related to lifestyle diseases of obesity, type 2 diabetes and metabolic syndrome.
Research
Many Healthy LungsIn partnership with Derbarl Yerrigan Health Service and the Broome Regional Aboriginal Medical Service, we aim to improve Aboriginal lung health by determining for the first time the baseline lung function of Aboriginal Australians.
Research
Whole-cell pertussis vaccine in early infancy for the prevention of allergyThis is a protocol for a Cochrane Review (intervention). The objectives were to assess the efficacy and safety of whole‐cell pertussis (wP) vaccinations in comparison to acellular pertussis (aP) vaccinations in early infancy for the prevention of atopic diseases in children.
Research
The mechanism of deep inspiration-induced bronchoprotection: Evidence from a mouse modelIn healthy individuals, deep inspirations (DIs) taken prior to a bronchial challenge reduce the bronchoconstrictor response, which is termed...
Research
The measurement properties of tests and tools used in cystic fibrosis studies: a systematic reviewThere is no consensus on how best to measure responses to interventions among children and adults with cystic fibrosis (CF). We have systematically reviewed and summarised the characteristics and measurement properties of tests and tools that have been used to capture outcomes in studies among people with CF, including their reliability, validity and responsiveness. This review is intended to guide researchers when selecting tests or tools for measuring treatment effects in CF trials. A consensus set of these tests and tools could improve consistency in how outcomes are captured and thereby facilitate comparisons and synthesis of evidence across studies.
Research
Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation, and airways hyperresponsiveness in mice exposed to house dust mite extractExcessive production, secretion, and retention of abnormal mucus is a pathological feature of many obstructive airways diseases including asthma. Azithromycin is an antibiotic that also possesses immunomodulatory and mucoregulatory activities, which may contribute to the clinical effectiveness of azithromycin in asthma.