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Research

Comparative drug screening in NUT midline carcinoma

The NUT midline carcinoma (NMC) is a rare but fatal cancer for which systematic testing of therapy options has never been performed.

Research

The concentration of iron in real-world geogenic PM10 is associated with increased inflammation and deficits in lung function in mice

Mineral dusts in the occupational setting are associated with poor lung health, however very little is known about the impact of heterogeneous community...

Research

Do emotional and behavioural difficulties in primary school predict adolescent victimisation trajectories?

The results of this study suggest whole-school bullying intervention programmes need to occur before students reach secondary school.

Research

Gender and the active smoking and high-sensitivity C-reactive protein relation in late adolescence.

This study examines the effect of smoking on high-sensitivity CRP (hs-CRP) levels, and the interactive effects of sex and OC use on this relationship in an...

Research

Comment on "Drug discovery: Turning the titanic"

We propose that the molecular and cellular events that govern a resolving, rather than an evolving, disease may reveal new druggable pathways.

Research

Rett Syndrome: Revised diagnostic criteria and nomenclature

The purpose of this work was to revise and clarify 2002 consensus criteria for the diagnosis of RTT in anticipation of treatment trials.

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Tumor Antigen Cross-Presentation and the Dendritic Cell: Where it All Begins?

Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that are critical for the generation of effective cytotoxic T lymphocyte (CTL) responses;

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Value of serology in predicting Pseudomonas aeruginosa infection in young children with cystic fibrosis

erology, predicting, Pseudomonas aeruginosa infection, young children, cystic fibrosis

Research

Contribution of an intrinsic lag of continuous glucose monitoring systems to differences in measured and actual glucose concentrations

Current continuous glucose monitoring (CGM) systems measure glucose levels in the interstitial fluid to estimate blood glucose concentration.

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Testing a new cognitive behavioural treatment for obesity

It is remarkably difficult for people with obesity to maintain a new lower weight following weight loss.