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Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEPOur results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells
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Comparable glycemic outcomes for pediatric type 1 diabetes patients in metropolitan and non-metropolitan regions of Western Australia: A population-based studyThis study reports similar glycemic outcomes for patients attending diabetes clinics in metropolitan and non-metropolitan areas of WA
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Effects of Dietary Acute Tryptophan Depletion (ATD) on NPY Serum Levels in Healthy Adult Humans Whilst Controlling for Methionine Supply-A Pilot StudyAcute tryptophan depletion, and therefore, diminished substrate availability for brain 5-HT synthesis did not lead to significant changes in serum neuropeptide Y concentrations over time
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Independent and combined effects of airway remodelling and allergy on airway responsivenessThere was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the presence of allergy
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Defining relevant hypoglycemia measures in children and adolescents with type 1 diabetesAs the choices of therapies in diabetes care multiply, it is essential to standardize the approach to measuring and recording hypoglycemia risk
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Determinants of a dietary pattern linked with greater metabolic risk and its tracking during adolescenceAlthough growing evidence suggests that dietary patterns associated with noncommunicable disease in adulthood may develop early in life.
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Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profilesthe association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories
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Nature play and fundamental movement skills training programs improve childcare educator supportive physical activity behaviorBoth the Nature play and fundamental movement skills professional development programs were effective in improving educators’ self-efficacy to engage children
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The incidence, prevalence and clinical features of MECP2 duplication syndrome in Australian childrenMECP2 duplication syndrome is a rare but important diagnosis in children because of the burden of respiratory illness and recurrence risk
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Trans and gender diverse young people's attitudes towards game-based digital mental health interventions: A qualitative investigationThis paper reports on trans and gender diverse young people's attitudes towards digital games and game-based digital mental health interventions