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Previous studies have reported an association between low birthweight and elevated blood pressure (BP) in adulthood, but few have examined the relationship between foetal growth and adult BP.
The airway smooth muscle (ASM) layer thickens during development. Identifying the mechanism(s) for normal structural maturation of the ASM reveals pathways susceptible to disease processes. This study characterized thickening of the ASM layer from foetal life to childhood and elucidated the underlying mechanism in terms of hypertrophy, hyperplasia and extracellular matrix (ECM) deposition.
Dedicated to preventing and managing chronic conditions in children, such as respiratory disease, diabetes, and cancer. This theme focuses on research to reduce the long-term impact of these conditions on quality of life and healthcare systems.
The Advancing Innovation in Respiratory (AIR) Health Team is a multi-disciplinary group with skills in clinical medicine, physiology, psychology, and in cellular and molecular biology, that are committed to improving the lives of children with respiratory diseases and their families.
The AREST CF project focuses on the assessment, treatment and prevention of CF lung disease in children under the age of seven.
Researchers are able to track the progress of lung disease through a comprehensive longitudinal set of biological samples, images and data archives.
Our team aims to optimise lung health early in life to ensure the best possible health outcomes later in life.
The Children's Diabetes Centre's research into Type 1 diabetes, childhood onset Type 2 diabetes and obesity aims to improve the lives of children and adolescents affected by these conditions.
Our research focuses on what are the best ways for patients with Type 1 Diabetes to exercise safely. We aim to develop clinical guidelines that provide improved advice for patients and educate patients on how to prevent hypos during and after exercise.
This study will tell us if the use of a hybrid closed loop system can improve awareness of hypoglycaemia.