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Burkholderia pseudomallei evades Nramp1 (Slc11a1)- and NADPH oxidase-mediated killing in macrophages and exhibits Nramp1-dependent virulence gene expressionHere we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1+) control the net replication of B. thailandensis, but not B. pseudomallei.
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Rheumatic Heart Disease Severity, Progression and Outcomes: A Multi‐State ModelThe prognosis of young Indigenous Australians diagnosed with severe RHD is bleak; interventions must focus on earlier detection and treatment
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Young people with intellectual disability transitioning to adulthood: Do behaviour trajectories differ in those with and without down syndromeChanges in emotional and behavioural problems for young people with intellectual disability with and without Down syndrome as they transition into adulthood
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CAGEd-oPOSSUM: motif enrichment analysis from CAGE-derived TSSsCAGEd-oPOSSUM can identify transcription factors that act as key regulators of genes involved in specific mammalian cell and tissue types
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Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemiaBiological changes associated with T-ALL relapse and resistance are stochastic and highly individual
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Hospital admission for infection during early childhood influences developmental vulnerabilities at age 5 yearsThis study demonstrates a pervasive effect of early life infections that require hospital admission on multiple aspects of early child development
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Does somatosensation change with age in children and adolescents? A systematic reviewSomatosensory modalities, such as touch, proprioception and haptic ability, greatly influence the achievement of developmental milestones for children.
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Adolescent and young adult medicine in Australia and New Zealand: towards specialist accreditationThe RACP is advancing a three-tier strategy to build greater specialist capacity and sustain leadership in adolescent and young adult medicine
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What bridges the gap between self-harm and suicidality? The role of forgiveness, resilience and attachmentThere is a lack of understanding of why some people who self-harm escalate to suicidal behaviour when others do not. Psychological factors such as attachment...
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Helicobacter pylori overcomes natural immunity in repeated infectionsHelicobacter pylori infection does not promote an immune response protective against future reinfection