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The collective impact of rare diseases in Western Australia: An estimate using a population-based cohort

This cohort study provides new evidence of a disparity between the proportion of the population with rare diseases and their combined health-system costs

Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infection

Dysfunction of T follicular-helper cells is a possible cause of impaired germinal centre and IgG antibody responses in individuals with HIV

Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.

We propose that this system provides a model for the differentiation and adaptation of monocytes entering the intestinal lamina propria.

Transcription start site profiling of 15 anatomical regions of the Macaca mulatta central nervous system

We believe this data represents a useful resource to understand the central nervous system in macaque.

The Prevalence of Stimulant and Antidepressant Use by Australian Children and Adolescents

A minority of 4- to 17-year-olds with ADHD and major depressive disorder were being treated with stimulant or antidepressant medication

End-inspiratory molar mass step correction for analysis of infant multiple breath washout tests

We aimed to evaluate the use of the EIMM-step method in a broad range of infants.

Patterns of multiple risk exposures for low receptive vocabulary growth 4-8 years in the Longitudinal Study of Australian Children

Our results demonstrate a range of multiple risk profiles in a population-representative sample of Australian children and highlight the mix of risk factors faced by children

Introducing ‘Young Minds Matter’

This article describes the survey, the response rates achieved and the representativeness of the sample for the Young Minds Matter survey

Suicidal behaviours: Prevalence estimates from the second Australian Child and Adolescent Survey of Mental Health and Wellbeing

Mental disorders should be a leading intervention point for suicide prevention both in the primary health sector and in the mental health sector specifically

Self-harm: Prevalence estimates from the second Australian Child and Adolescent Survey of Mental Health and Wellbeing

The demonstrated higher risks in young people for continued harm or possible death support the need for ongoing initiatives to reduce self-harm