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Research

Down Syndrome

Down syndrome, also known as Trisomy 21, is one of the most common chromosome abnormalities in humans. It occurs when a child's cells end up with 47 chromosomes instead of the usual 46. Down syndrome causes intellectual disability and other physical and learning challenges.

Research

Anaphylaxis

Anaphylaxis is rapid onset severe allergic reaction to an allergen. These allergens are most commonly food, insects, or medication. Anaphylactic reactions are serious and can be life-threatening.

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Gene-based outcome prediction in multiple cohorts of pediatric T-cell acute lymphoblastic leukemia: a Children's Oncology Group study

Continuous complete clinical remission in T-cell acute lymphoblastic leukemia (T-ALL) is now approaching 80% due to the implementation of aggressive...

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Age at diagnosis of birth defects

Many birth defects surveillance programs ascertain cases of birth defects diagnosed beyond 1 year of age.

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Reliability and validity of the Conditional Goal Setting in Eating Disorders Scale (CGS-EDS) among adults with eating disorders

The aim of this study was to develop and validate a self-report measure of Conditional Goal Setting (CGS) for use among individuals with eating disorders...

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Association between socioeconomic status and the development of asthma: analyses of income trajectories

Using data on 2868 children born in the Western Australian Pregnancy Cohort (Raine) Study, we examined the association between changes in family...

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Th2-polarisation of cellular immune memory to neonatal pertussis vaccination

Current infant vaccination against pertussis in North America and Australia requires three doses of vaccines including diphtheria, tetanus and acellular...

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Free testosterone levels in umbilical-cord blood predict infant head circumference in females

Fetal androgens influence fetal growth as well as postnatal neurocognitive ability