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Substantial spatial clustering of notified tuberculosis was detected at region, zone and district level in Ethiopia

We review the Group A Streptococcus Human infection studies and present the study protocol for a dose-ranging inpatient study in healthy adults

Our maps provide a baseline for measuring change and a mechanism to guide interventions during the era of the Sustainable Development Goals

increased adherence to penicillin prophylaxis is associated with reduced acute rheumatic fever recurrence and a likely reduction in mortality

Direct and indirect effects on pneumococcal carriage post-PCV10 are likely to result in reductions in pneumococcal disease, including in infants too young to be vaccinated

Population-based primary prevention of ARF through sore throat management may be effective in well-resourced settings like New Zealand

Intramuscular administration of novel acetylated peptide-protein conjugate vaccine candidate MJ8VAX was demonstrated to be safe and immunogenic

This Group A Streptococcus OPKA assay has the potential to provide a robust and reproducible platform to accelerate GAS vaccine development.

Our analysis shows that early and late intervention to support household income have equal importance with regards to significance of impact.

These findings highlight the critical need to evaluate the efficacy of future pneumococcal vaccine programs in the Australian Indigenous populations that recommend repeated doses of 23vPPV.