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Research

Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study

We review the Group A Streptococcus Human infection studies and present the study protocol for a dose-ranging inpatient study in healthy adults

Research

Discrete choice experiment to evaluate preferences of patients with cystic fibrosis among alternative treatment-related health outcomes: A protocol

The aim of this study is to identify and quantify the preferences of patients with cystic fibrosis regarding treatment outcomes

Research

Functional genomics in cancer immunotherapy: Computational approaches for biomarker and drug discovery

This review explores computational strategies to yield biological insight into the processes involved in the immunotherapeutic response

Research

Validation of monoclonal anti-PKC isozyme antibodies for flow cytometry analyses in human T cell subsets and expression in cord blood T cells

We have undertaken to validating the specificity of commercially available antibodies marketed for flow cytometry to measure PKCα, βI, βII, δ, ε, η, θ, ζ, ι/λ and μ

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Agreement between units of measure for paediatric antibiotic utilisation surveillance using hospital pharmacy supply data

Agreement between the DDD and vial-based measures of use supports the use of DDD for select antibiotics that may be targeted by antimicrobial stewardship programs

Research

Reduced heart rate variability in adults with autism spectrum disorder

Our data suggest an overall dysregulation in resting autonomic activity in adults with autism spectrum disorder

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Call for a national sore throat guideline

Australia needs a single national pharyngitis guideline to assist in providing rational, consistent and timely antibiotic treatment to patients at high risk of ARF

Research

Gender-affirming hormones and surgery in transgender children and adolescents

This Review explores the available published evidence on gender-affirming cross-sex hormone and surgical interventions in transgender children

Research

The public health control of scabies: priorities for research and action

Scabies causes considerable morbidity and leads to severe bacterial infection and immune-mediated disease

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Overcoming the challenges of caring for a child with foetal alcohol spectrum disorder: a Pilbara community perspective

The caregivers in this study have gained valuable knowledge and wisdom through caring for a child with FASD