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Integrate, Identify, Intervene (Triple I Project): Identifying opportunities for preventing respiratory infections in children through integrating population-based health and laboratory data

Christopher Hannah Blyth Moore MBBS (Hons) DCH FRACP FRCPA PhD OAM BSc (Hons) GradDipClinEpi PhD Centre Head, Wesfarmers Centre of Vaccines and

Investigating the role of Neutrophils in Multiple Sclerosis

Neutrophils are a type of immune cell that can trigger inflammation and may play a role in the development of MS.

Pilbara FASD Project

Glenn Martyn Pearson Symons BA (Education) PhD Candidate B.A. (Hons) PhD. Director of First Nations Strategy and Leadership; Head, First Nations

Germs!

Discover resources and science activities for kids for the topic 'Germs!'.

Breakthrough in antibiotic discovery opens Pandora's Box

Although a staple of modern medicine, the benefits of antibiotics are waning thanks to overuse and the increasing ability of bacteria to dodge them – known as antimicrobial resistance (AMR).

Early detection helps delay onset of diabetes

A world-first study led by Dr Aveni Haynes at The Kids’ Rio Tinto Children’s Diabetes Centre, is helping to detect early changes in blood sugar levels.

SToP-ping skin sores in the Kimberley

More than 3,000 skin checks have been undertaken as part of a large clinical trial in WA’s Kimberley region aimed at halving the burden of skin sores in school-aged Aboriginal children.

Neonatal and infant mortality after maternal influenza and pertussis vaccination: Probabilistically linked cohort study

Maternal influenza and pertussis vaccination is an important strategy to reduce morbidity and mortality in infants. Previous vaccine safety studies have mostly focused on the association between maternal vaccination and fetal death.

Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions

Since their first detection in 2010, Plasmodium falciparum malaria parasites lacking the P. falciparum histidine-rich protein 2 gene (pfhrp2) have been observed in 40 of 47 surveyed countries, as documented by the World Health Organization. These genetic deletions reduce detection by the most widely used rapid diagnostic tests, prompting three countries to switch to alternative diagnostics.

What goes up must come down: dynamics of type 1 interferon signaling across the lifespan

Type 1 interferons (T1IFNs) are typically expressed in low concentrations under homeostatic conditions, but upon pathogenic insult or perturbation of the pathway, these critical immune signaling molecules can become either protectors from or drivers of pathology. While essential for initiating antiviral defense and modulating inflammation, dysregulation of T1IFN signaling can contribute to immunopathology, making it and its associated pathways prime targets for immune evasion and disruption by pathogens.