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Research

Choosing primary endpoints for clinical trials of health care interventions

This narrative review describes the evolution, range and relative strengths and weaknesses of endpoints used in late phase trials

Research

The effect of upgrades to childcare outdoor spaces on preschoolers’ physical activity: Findings from a natural experiment

This natural experiment investigated the influence of early childhood education and care outdoor physical environment upgrade on preschoolers' physical activity

Research

Antibiotics versus topical antiseptics for chronic suppurative otitis media

Treatment of chronic suppurative otitis media with topical antibiotics probably results in an increase in resolution of ear discharge compared with boric acid

Research

Genetic determinants of paediatric food allergy: A systematic review

We systematically reviewed the literature on the genetic basis of food allergy, identifying areas for further investigation

Research

Coffee and tea consumption during pregnancy and risk of childhood acute myeloid leukemia: A Childhood Leukemia International Consortium (CLIC) study

We investigated the potential association of maternal coffee and tea consumption during pregnancy with childhood acute myeloid leukemia risk

Research

Quorum Sensing Signaling Alters Virulence Potential and Population Dynamics in Complex Microbiome-Host Interactomes

Genome sequencing and phylogenetic analysis of a quorum sensing positive Psychrobacter isolate identified several quorum sensing associated systems

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An assessment of computer-generated stimuli for use in studies of body size estimation and bias

Our results show that perception of body size for computer-generated stimuli was non-linear

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Investing in school readiness: A comparison of different early childhood education pathways in rural Indonesia

This paper documents that children in rural Indonesia participate in a great variety of early childhood education pathways

Research

Method of bacterial killing differentially affects the human innate immune response to Staphylococcus epidermidis

In vitro investigations of human innate immune responses to extracellular bacteria commonly utilise killed preparations in preference to live organisms

Research

House dust mite allergens in asthma and allergy

IgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against