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Research

Maternal Smoking During Pregnancy Induces Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic Risk

This study demonstrates a critical timing of cigarette smoke exposure over the life course for establishing persistent changes in DNA methylation into adolescence

Research

Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children

Bacterial airway microbiome is highly variable in early life and its role in wheeze remains less clear than viral influences

Research

Using pneumococcal carriage studies to monitor vaccine impact in low- and middle-income countries

We review the role of pneumococcal carriage studies for the evaluation of PCVs in LMICs and discuss optimal methods for conducting these studies

Research

A framework for the management of the pediatric airway

A simple, time critical, and pediatric-specific airway management approach will help to reduce airway-related pediatric morbidity and mortality

Research

The microbiology of impetigo in Indigenous children

Prevalence and antimicrobial resistance of impetigo pathogens in a randomised, controlled trial of impetigo treatment conducted in remote Indigenous communities

Research

Acute rheumatic fever and rheumatic heart disease: Incidence and progression in the Northern Territory of Australia 1997 -2010

The reduction in ARF recurrence indicates that the RHD control program has improved secondary prophylaxis; a decline in RHD incidence is expected to follow.

Research

International collaboration to assess the risk of Guillain Barré Syndrome following Influenza A (H1N1) 2009 monovalent vaccines.

The global spread of the 2009 novel pandemic influenza A (H1N1) virus led to the accelerated production and distribution of monovalent 2009 Influenza A...

Research

Size-Dependent Uptake of Particles by Pulmonary Antigen-Presenting Cell Populations

The respiratory tract is an attractive target organ for novel diagnostic and therapeutic applications with nano-sized carriers, but their immune effects and...

Research

Species-Specific and Cross-Reactive IgG1 Antibody Binding to Viral Capsid Protein 1 (VP1) Antigens of Human Rhinovirus Species A, B and C

Human rhinoviruses (HRV) are associated with upper and lower respiratory illnesses, including severe infections causing hospitalization in both children...

Research

Exploring the potential to use data linkage for investigating the relationship between birth defects and prenatal alcohol exposure

There was a significant association between maternal alcohol-related diagnoses recorded during pregnancy and ARBD, with an attributable fraction of 0.57%.