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Research

New genetic loci link adipose and insulin biology to body fat distribution

Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing...

Research

Early pulmonary inflammation and lung damage in children with cystic fibrosis

Airway inflammation and infection are present from early in life, often before children are symptomatic.

Research

Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014

The Influenza Complications Alert Network (FluCAN) is a sentinel hospital-based surveillance programme operating in all states and territories in Australia

Research

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability

HRV-1B infection directly alters human airway epithelial TJ expression leading to increased epithelial permeability potentially via antiviral response of IL-15

Research

Successful Treatment of Congenital Erythroleukemia With Low-Dose Cytosine Arabinoside

We report a term male with congenital acute erythroleukemia who achieved sustained remission with low-dose cytosine arabinoside alone

Research

Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

Differential network analysis of allergen-induced CD4 T cell responses can unmask covert disease-associated genes and pin point novel therapeutic targets

Research

Missing voices: Profile and extent of acquired communication disorders in Aboriginal and non-Aboriginal adult stroke survivors in Western Australia

The needs of Aboriginal stroke patients with acquired communication disorder should inform appropriate service design for speech pathology and rehabilitation

Research

Prevention of Allergy/Asthma - New Strategies

This review focuses on the scientific rationale for early intervention aimed at asthma prophylaxis and discusses therapeutic approaches

Research

ViPAR: A software platform for the Virtual Pooling and Analysis of Research Data

ViPAR is a secure, flexible and powerful analysis platform built on open source technology that is currently in use by large international consortia

Research

Declining transition rates to psychotic disorder in "ultra-high risk" clients: Investigation of a dilution effect

Later ultra-high risk psychosis cohorts presented with different clinical intake characteristics than earlier cohorts