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The Pregnancy and Early Life Immunology team's overall research vision is targeted towards understanding immunological development during early life.
This study aims to investigate the cellular and molecular profiles of the immune system in infants at high/low risk for Autism, as determined through clinical assessment.
We are studying immune cells from identical twins of which one suffers and one does not suffer from allergic disease to identify specific mechanisms that may play important roles in disease development.
This study is designed to identify the specific unique immune cell response that occurs in these children with recurrent disease.
Studies in Europe show exposure of pregnant women to high levels of microbial products stimulate immune function maturation in their offspring
The study aims to identify the mechanism for this so that this knowledge can be used to better treat asthma and allergies in both males and females.
This project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.
This work is the first step to develop safe treatments for pregnant mums to protect against preterm delivery and low birth weight caused by maternal infections.
Food allergy is a major public health challenge in Australia. Despite widespread uptake of infant feeding and allergy prevention guidelines the incidence of peanut allergy in infants has not fallen, and prevalence of peanut allergy in school-aged children continues to rise. Therefore, effective and accessible treatments for peanut allergy are required.
Persistent regional and systemic inflammation may promote pain and hyperalgesia in complex regional pain syndrome. In this study, we investigated whether stimulation of α1-adrenoceptors on peripheral blood mononuclear cells might contribute to this inflammatory state.