Infant vaccination with 3 doses of PCV10 or PCV13 is safe and immunogenic in a highly endemic setting
Combining elevated CRP with the presence or absence of clinical signs/ symptoms differentiates definite bacterial from presumed viral pneumonia bette…
Respiratory viruses, particularly respiratory syncytial virus and human metapneumovirus, are major contributors to pneumonia in Australian children
PPV is immunogenic in 9-month-old children at high risk of pneumococcal infections and does not affect the capacity to produce protective immune resp…
PCV10 did not reduce NTHi density in the nasopharynx or middle ear, and was associated with increased pneumococcal nasopharyngeal density
We observed an association between Type III DNA methyltransferase presence and Otitis Media-associated middle ear isolates
These data provide evidence that otitis-prone children do not have impaired functional cell mediated immunity
Pneumonia is the leading cause of childhood morbidity and mortality globally.
We aim to determine the contribute of bacteria and virus to childhood CAP to inform further development of effective strategies.
We have previously demonstrated that mice exposed to geogenic dust PM10 experienced an exacerbation of inflammatory responses to influenza A virus.