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Bacteriophages (phages) are viruses that selectively kill bacteria and offer a promising option to address the growing global pandemic of antimicrobial-resistant infections. However, phage therapy does not easily align with traditional regulatory pathways designed for fixed-composition chemical drugs or biologics with fixed non-evolving compositions.
Preterm birth is associated with lifelong respiratory sequelae, yet our understanding of lung function trajectories across the lifespan remains limited. We aimed to identify patterns of spirometry development from childhood to early adulthood in survivors of very preterm birth using novel data-driven methods.
Wheezing and asthma exacerbations are leading causes of pediatric hospital admissions. Predicting which children will experience persistent exacerbations remains challenging. Prior research has identified immune endotypes in the nasal epithelium of children with acute asthma and wheezing, characterized by varying balances of interferons and inflammatory markers. Notably, children exhibiting low interferon responses coupled with high inflammation are at an increased risk for recurrent respiratory exacerbations.
The study aimed to evaluate the experiences of participants involved in co-production to develop a National Framework for assessing children's functional strengths and support needs. The National Framework was developed to guide professionals when working with children aged 0-12 years, including children who do and do not have one or more diagnosed condition(s), and their families in Australia and inform good policy across health, education, disability, and community support sectors.
Aleksandra Filipovska FAA, FAHMS BSc PhD Louis Landau Chair in Child Health Research; NHMRC Leadership Fellow; Deputy Director, ARC Centre of
Researchers in the Child Health, Development and Education Team support a number of projects financed by the World Bank and the Global Partnership for Education to promote early learning and development in Lao People’s Democratic Republic (PDR).
Tobias Jenny Strunk Mountain Other Investigators MD, PhD, FRACP MBA MClinEpi Head, Neonatal Health Program Manager, Neonatal Health / Protect Trial
The Kids Research Institute Australia has secured a State Government grant to prepare a nasal therapy designed to prevent childhood ear infections for a world-first clinical trial.
Ground-breaking WA-led study, Early Moves has hit a major milestone, with 3,000 participants successfully recruited over a four-year period.
ORIGINS is moving to virtual appointments and couriers to collect home samples during the June 2021 Perth lockdown.