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The Chronobiology team works to understand the factors that contribute to poor lung and heart function in newborn infants and find ways to prevent heart and lung disease.

The END RHD CRE focuses priority research projects that will help achieve the singular target of producing the Endgame Strategy.

Research

This study will investigate the why disease is worse in infants and how early life viral infection impacts the developing immune system.

News & Events

Between 3rd - 5th May 2018, researchers from Australia, New Zealand, South Africa, and the United States (representing their Uganda collaboration) convened in Fremantle, Western Australia to attend the Strep A Spectrum Meetings: from Science to Strategy.

Focus Area

The Early Environment research theme consists of four programs: Immunobiology and Immunotherapeutic, Early Life and Life Course Health, Infection and Vaccines, and End RHD.

News & Events

Learn more about the background and motivations of END RHD CRE Research Fellow Simone Reynolds.

Research

The relationship between physical activity and child health and development is well-documented, yet the extant literature provides limited causal insight into the amount of physical activity considered optimal for improving any given health or developmental outcome.

Research

We aimed to evaluate the effect of undernutrition on sputum culture conversion and treatment outcomes among people with multidrug-resistant tuberculosis.

Research

Lung transcriptomics studies in asthma have provided valuable information in the whole lung context, however, deciphering the individual contributions of the airway and parenchyma in disease pathogenesis may expedite the development of novel targeted treatment strategies. In this study, we performed transcriptomics on the airway and parenchyma using a house dust mite (HDM)-induced model of experimental asthma that replicates key features of the human disease.