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The Wittenoom legacy

The legacy of Wittenoom has extended beyond the mine and the town, and is still evident more than 50 years after the closure of the mine

COPD-related modification to the airway epithelium permits intracellular residence of nontypeable haemophilus influenzae

Our findings indicate that COPD, cigarette smoke and macrolide antibiotics potentiate the susceptibility to persistent intracellular NTHi

Raising strong, solid Koolunga: Values and beliefs about early child development among Perth's Aboriginal community

We detail the unique findings from an Aboriginal early child development research project with a specific focus on the Nyoongar/Aboriginal community of Perth

Literacy and Numeracy Underachievement in Boys and Girls With ADHD

Children with ADHD are disadvantaged from an early age in key areas of learning, and this risk increased with reduction in gestational age at birth

Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia

Our study provides evidence that OT-82 is a promising new therapeutic strategy for a broad spectrum of high-risk pediatric acute lymphoblastic leukemia

Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?

Baseline signatures might contribute to identifying interventional targets to be modulated prior to vaccination in order to improve vaccination responses

Airway Epithelial Cell Immunity Is Delayed During Rhinovirus Infection in Asthma and COPD

We propose that propensity for viral exacerbations of asthma and COPD relate to delayed expression of epithelial cell innate anti-viral immune genes

Understanding obesity among companion dogs: New measures of owner's beliefs and behaviour and associations with body condition scores

The findings provide a method for assessing a wide range of factors that may be associated with obesity among companion dogs

Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma

Findings provide further proof of concept that pharmacological targeting of airway smooth muscle thickness will be beneficial and may be facilitated by azithromycin