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Research
Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothersWe sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception.
Research
Adversity and resilience amongst resettling Western Australian paediatric refugeesRefugee children have complex backgrounds with exposure to multiple traumatic events.
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Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed ScreensThe poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput.
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Geographical disparities in emergency department presentations for acute respiratory infections and risk factors for presentingOne in four ED presentations in WA children are for ARIs, representing a significant out-of-hospital burden with some evidence of geographical disparity
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Determining the pneumococcal conjugate vaccine coverage required for indirect protection against vaccine-type pneumococcal carriage in low and middle-income countriesWe will investigate the relationship between PCV coverage and VT carriage among undervaccinated children in Asia and the Pacific
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Online interventions for the mental health needs of trans and gender diverse young peopleMembers of our research team have done an online survey (Trans Pathways) exploring the mental health and care pathways of gender diverse youth in Australia.
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Oral prednisolone in preschool children with virus-associated wheeze: A prospective, randomised, double-blind, placebo-controlled trialPreschool children often have episodes of virus-associated wheeze and assessing efficacy of corticosteroids for paediatric wheeze exacerbations is inconcludsive
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Sustained participation in annual continuous quality improvement activities improves quality of care for Aboriginal and Torres Strait Islander childrenTo determine whether participation in the CQI Audit and Best Practice for Chronic Disease programme improved care and outcomes for Indigenous children.
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Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in childrenIn this study, we aimed to investigate the usefulness of miRNAs as biomarkers in diagnosing and predicting children with congenital heart defects (CHD), particularly in the context of multiple subtypes of CHD.
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Independent and combined effects of airway remodelling and allergy on airway responsivenessThere was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the presence of allergy