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Research

The triple challenges associated with age-related comorbidities in Down syndrome

Major increases in the survival of people with Down syndrome during the last two generations have resulted in extended periods of adulthood requiring...

Research

Lower fructose intake may help protect against development of nonalcoholic fatty liver in adolescents with obesity

Although obesity is a major risk factor for nonalcoholic fatty liver (NAFL), not all individuals with obesity develop the condition, suggesting that other...

Research

Investigation of the Cross-National Equivalence of a Measurement of Early Child Development

The present study examined the psychometric properties of the domains of the 48-item EDI and the invariance of the measurement models of the domains of the...

Research

Lung function, airway inflammation, and polycyclic aromatic hydrocarbons exposure in mexican schoolchildren: A pilot study

To determine the association of exposure to polycyclic aromatic hydrocarbons (PAHs) with lung function and pH of exhaled breath condensate (EBC) in Mexican...

Research

Genetic susceptibility to otitis media in childhood

Reviewed in this article these studies have identified positive association at 21 genes with association at five of these replicated in independent populations.

Research

A genomics-based approach to assessment of vaccine safety and immunogenicity in children

This methodology has significant potential to identify covert interactions between inflammatory pathways triggered by vaccination, and as such may be a...

Research

IgG Responses to Pneumococcal and Haemophilus Influenzae Protein Antigens Are Not Impaired in Children with a History of Recurrent Acute Otitis Media

Vaccines including conserved antigens from Streptococcus pneumoniae & nontypeable Haemophilus influenzae have the potential to reduce of otitis media.

Research

Recording a history of alcohol use in pregnancy: an audit of knowledge, attitudes and practice at a child development service

To assess the effectiveness of alcohol documentation and to measure the practice of health practitioners in relation to asking about alcohol and pregnancy.

Research

No dose-dependent increase in fracture risk after long-term exposure to high doses of retinol or beta-carotene

This intervention study found no increase in fracture risk among 2,322 adults who took a controlled, high-dose retinol supplement for as long as 16 years.

Research

Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenza

These findings reinforce current recommendations for annual influenza vaccination, particularly those at greatest risk of influenza disease.