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Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis

The antirelapse efficacy of primaquine is related to the total dose administered, whereas the risks of haemolysis and gastrointestinal intolerance are associated with the daily dose administered. National Malaria Control Programmes require local information on efficacy, tolerability and safety to optimize antimalarial treatment policies for Plasmodium vivax malaria control and elimination efforts.

Prognostic Accuracy of BPD Definitions for Long-Term Outcomes in Preterm Infants: A Systematic Review

Since the first description of bronchopulmonary dysplasia (BPD), multiple definitions to diagnose BPD and its grading have been published. Several studies have compared the predictive performance of these definitions for long-term outcomes. The objective was to identify the BPD definition with the optimal predictive performance for long-term respiratory and neurological outcomes in preterm infants.

The impact of obesity on influenza Vaccine immunogenicity - A systematic review

Influenza vaccines are important for reducing the burden of influenza, particularly for populations at risk of more severe infections. Obesity is associated with increased influenza severity and therefore individuals with obesity are often specifically recommended for annual influenza vaccination. Obesity is also associated with an altered inflammatory profile, which may influence vaccine responses. This systematic review aimed to evaluate the evidence for any association between obesity and influenza vaccine immunogenicity.

Non-Suicidal Self-Injury and Outcome Expectancies: The Roles of Self-Efficacy, Cognitive Reappraisal, and Expressive Suppression

According to the Cognitive Emotional Model of Non-Suicidal Self-Injury (NSSI), this behavior is governed by a complex interplay of NSSI-related cognitions (i.e., a person's expected outcomes of self-injury and self-efficacy to resist NSSI) and emotion-regulatory strategies (i.e., cognitive reappraisal and expressive suppression). To empirically test this proposition, the current study examined the moderating roles of self-efficacy to resist NSSI, cognitive reappraisal, and expressive suppression in the relationships between outcome expectancies and NSSI frequency among university students.

Dog ownership, dog walking, and physical function in mid-older adults: Findings from the HABITAT cohort study

To examine the longitudinal effects of dog ownership and dog walking on self-reported and objective measures of physical function in mid- to older-aged adults.

Quantitative measures of subjective wellbeing for adolescents: a scoping review and synthesis of comparable data

Efforts to promote adolescent wellbeing are of increasing global interest. Although the ability to measure wellbeing is essential for identifying disparities between and within populations, and for tracking progress in improving wellbeing, the best way to measure this elusive concept in adolescents is unclear.

Health literacy scale for English-speaking children: translation and validation of the HLS-Child-Q15-EN

To translate and validate the HLS-Child-Q15, a relatively short questionnaire for assessing health literacy in children originally validated in German, into English to make it accessible to a large population of English-speaking children.

Impact of Host and Bacterial Metabolism on Antibiotic Susceptibility

Antimicrobial resistance (AMR) is a global healthcare emergency, directly causing 1.3 million deaths per year and predicted to increase dramatically over the coming decades. Understanding the molecular mechanisms underpinning antibiotic resistance is central to approaches for AMR surveillance and diagnosis in a clinical laboratory.

Experiences and Recognition of Intimate Partner Violence among a Community-Sample of LGBTIQA + People in Western Australia

LGBTIQA + people experience intimate partner violence (IPV) at higher rates than non-LGBTIQA + people but under-utilize professional support services, and the reasons for this are poorly understood. This study examined IPV experiences, recognition of IPV, service utilization, and support needs among a self-selected sample of 523 LGBTIQA + adults in Western Australia.

Cardiometabolic Biomarkers and Prediction of Kidney Disease Progression: The eGFR Cohort Study

Traditional markers modestly predict chronic kidney disease progression in Aboriginal and Torres Strait Islander people. Therefore, we assessed associations of cardiometabolic and inflammatory clinical biomarkers with kidney disease progression among Aboriginal and Torres Strait Islander people with and without diabetes.