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Nanoparticle research is currently an area of considerable interest due to the potential applications both in industry and medicine.
The incidence of atopic disease has increased dramatically during recent decades and the potential immunoregulatory influence of the microbiota in these...
Meningococcal disease is caused by the bacteria Neisseria meningitidis, or 'meningococcus'. It is an uncommon but very serious disease that can result in death if not recognised and treated quickly.
Anthony Christopher David Ingrid Shannon Thomas Kicic Blyth Martino Laing Simpson Iosifidis BSc (Hons) PhD MBBS (Hons) DCH FRACP FRCPA PhD BSc PhD
Incomplete maturation of immune regulatory functions at birth is antecedent to the heightened risk for severe respiratory infections during infancy. Our forerunner animal model studies demonstrated that maternal treatment with the microbial-derived immune training agent OM-85 during pregnancy promotes accelerated postnatal maturation of mechanisms that regulate inflammatory processes in the offspring airways.
We aimed to delineate the effects of LPS and AMP on airway inflammation, and potential contribution to airway disease by measuring airway inflammatory responses
Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial...
Valued at a total of $440,000, the Wal-yan Respiratory Research Centre Inspiration Awards 2022 will support five cutting-edge research projects.
Human perinatal life is characterized by a period of extraordinary change during which newborns encounter abundant environmental stimuli and exposure to potential pathogens. To meet such challenges, the neonatal immune system is equipped with unique functional characteristics that adapt to changing conditions as development progresses across the early years of life, but the molecular characteristics of such adaptations remain poorly understood.
This project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.