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Showing results for "early lung health"

Sunny outlook for allergy-prone bub

Felix was one of 195 children to take part in Dr Debbie Palmer’s research into sunlight exposure, vitamin D and eczema.

Frankie and Friends app

Researchers at The Kids Research Institute Australia and University of Western Australia have recently published data describing the use of an attention training game designed for school-aged children diagnosed with autism spectrum disorder (ASD).

Reducing radiotherapy: new antibody gives hope for less toxic cancer treatment

WA Kids Cancer Centre is leading the charge to find innovative new treatments that will allow doctors to ‘dial down’ the amount of toxic treatments needed to fight cancer.

Parental origin of mutations

We hypothesised that MECP2 mutations occur predominantly on the male derived X chromosome.

The Mast Cell Study

Comparing how mast cells are “programmed” in allergic and non-allergic children at one year of age.

Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in supratentorial ependymoma

Supratentorial RELA fusion (ST-RELA) ependymomas (EPNs) are resistant tumors without an approved chemotherapeutic treatment. Unfortunately, the molecular mechanisms that lead to chemoresistance traits of ST-RELA remain elusive. The aim of this study was to assess RELA fusion-dependent signaling modules, specifically the role of the Hedgehog (Hh) pathway as a novel targetable vulnerability in ST-RELA.

Research roundup

Take a look at some of the published research to come out of the Children's Diabetes Centre recently.

RHD in Australia

Rheumatic heart disease (RHD) is a preventable,devastating condition that disproportionately affects Aboriginal and Torres Strait Islander Australians.

Important clinic update

There is lots of news to report from the clinic including holiday shutdown dates, appointment scheduling, staff updates, and more.

CRISPR-Cas9-generated PTCHD1 2489T>G stem cells recapitulate patient phenotype when undergoing neural induction

An estimated 3.5%-5.9% of the global population live with rare diseases, and approximately 80% of these diseases have a genetic cause. Rare genetic diseases are difficult to diagnose, with some affected individuals experiencing diagnostic delays of 5-30 years. Next-generation sequencing has improved clinical diagnostic rates to 33%-48%. In a majority of cases, novel variants potentially causing the disease are discovered.