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Research

Multi-modality monitoring of cystic fibrosis lung disease: the role of chest computed tomography

Stratification of monitoring protocols based on the risk profile of the patient can help us in the future to better care for people with Cystic Fibrosis.

Research

The gap in life expectancy from preventable physical illness in psychiatric patients in Western Australia

Despite knowledge about excess mortality in people with mental illness, the gap in their life expectancy compared with the general population has widened...

News & Events

Online safety for under 5's

eSafety Early Years program and resources -tips to support children and families in online safety

News & Events

Setting smart phone rules

Mobile phones are an important part of diabetes management but its also important to set some family rules for your child's technology use.

News & Events

T1D Mobile Health App

T1D Mobile Health App It is important for people living with type 1 diabetes (T1D) to engage in a physically active lifestyle, but it can be

News & Events

2018 workshop recap

The Children’s Diabetes Centre’s (CDC) annual workshop provided a great opportunity for diabetes researchers to get together in the one venue to showcase their work recently.

News & Events

Can protein lower the risk of hypos after exercise?

Participants are needed for a new study looking at whether protein after exercise can decrease the risk of delayed low blood glucose levels after exercise.

News & Events

Unwanted devices?

The PMH Diabetes and Endocrinology clinic is seeking donations of old Apple and android devices to pass on to families for CGM.

News & Events

2016 Events Calendar

Find all the events the Children's Diabetes Centre have scheduled for 2016.

Research

Tapasin assembly surveillance by the RNF185/Membralin ubiquitin ligase complex regulates MHC-I surface expression

Immune surveillance by cytotoxic T cells eliminates tumor cells and cells infected by intracellular pathogens. This process relies on the presentation of antigenic peptides by Major Histocompatibility Complex class I (MHC-I) at the cell surface. The loading of these peptides onto MHC-I depends on the peptide loading complex (PLC) at the endoplasmic reticulum (ER).