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Showing results for "Childhood interstitial lung disease "

WA, Queensland leading nation’s improvements in early childhood outcomes

Western Australia and Queensland are leading the nation when it comes to ensuring children have a good start at school, according to a study by researchers at The Kids Research Institute Australia.

Transcriptomic analysis of primary nasal epithelial cells reveals altered interferon signalling in preterm birth survivors at one year of age

Many survivors of preterm birth (<37 weeks gestation) have lifelong respiratory deficits, the drivers of which remain unknown. Influencers of pathophysiological outcomes are often detectable at the gene level and pinpointing these differences can help guide targeted research and interventions. This study provides the first transcriptomic analysis of primary nasal airway epithelial cells in survivors of preterm birth at approximately 1 year of age.

Adherence to Oral Targeted Anti-Lung Cancer Therapy: A Qualitative Interview Study

Oral targeted antineoplastic drugs (OTADs) are becoming more and more acceptable for lung cancer treatment due to their advantages such as the convenience of administration and milder side effects. However, medication adherence represents a major issue for prolonged OTAD treatment.

Is there a role for lung-protective ventilation in healthy children?

Lung-protective ventilation (LPV) has been adopted in the theater environment as a strategy to reduce pulmonary complications under anesthesia. Postoperative pulmonary complications are not infrequent and may have significant implications on the postoperative length of stay as well as the morbidity and mortality of pediatric patients.

Role of COL5A1 in lung squamous cell Carcinoma: Prognostic Implications and therapeutic potential

Lung squamous cell carcinoma (LUSC) is a significant health concern, characterized by a lack of specific therapies and limited treatment options for patients in advanced stages. This study aims to identify key molecules of prognostic importance in LUSC and provide an experimental foundation for their potential therapeutic applications.

Postnatal steroids as lung protective and anti-inflammatory in preterm lambs exposed to antenatal inflammation

Lung inflammation and impaired alveolarization precede bronchopulmonary dysplasia (BPD). Glucocorticoids are anti-inflammatory and reduce ventilator requirements in preterm infants. However, high-dose glucocorticoids inhibit alveolarization. The effect of glucocorticoids on lung function and structure in preterm newborns exposed to antenatal inflammation is unknown. We hypothesise that postnatal low-dose dexamethasone reduces ventilator requirements, prevents inflammation and BPD-like lung pathology, following antenatal inflammation.

Impact of fetal treatments for congenital diaphragmatic hernia on lung development

The extent of lung hypoplasia impacts the survival and severity of morbidities associated with congenital diaphragmatic hernia.

Pleural Plaques and the Risk of Lung Cancer in Asbestos-exposed Subjects

The presence of pleural plaques on radiologic imaging does not confer additional increase in the risk of lung cancer

Lung function, airway inflammation, and polycyclic aromatic hydrocarbons exposure in mexican schoolchildren: A pilot study

To determine the association of exposure to polycyclic aromatic hydrocarbons (PAHs) with lung function and pH of exhaled breath condensate (EBC) in Mexican...

High tidal volume ventilation does not exacerbate acid-induced lung injury in infant rats

The impact of mechanical ventilation with high VT-low PEEP in infant rats with preinjured lungs is unknown.