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Showing results for "Childhood interstitial lung disease "
Investigating the possible contributors to childhood lung disease by studying the epithelial cells from the nose at birth.
An NHMRC grant exploring epigenetic factors that affect wheezing and asthma development.
Rhinoviruses (RVs) can cause severe wheezing illnesses in young children and patients with asthma. Vaccine development has been hampered by the multitude of RV types with little information about cross-neutralization. We previously showed that neutralizing antibody (nAb) responses to RV-C are detected twofold to threefold more often than those to RV-A throughout childhood. Based on those findings, we hypothesized that RV-C infections are more likely to induce either cross-neutralizing or longer-lasting antibody responses compared with RV-A infections.
LIFECYCLE is a significant and visionary project to establish an integrated set of long-term world-wide cohorts and clinical trials, which can be investigated and compared across the full life of cohort participants.
Survivors of CDH may have significant adverse long-term medical and psychosocial issues that would be better recognised and managed in a multidisciplinary clinic
A new study to determine if it’s safe for children who were born preterm to attend day care officially commenced this month.
Many survivors of preterm birth (<37 weeks gestation) have lifelong respiratory deficits, the drivers of which remain unknown. Influencers of pathophysiological outcomes are often detectable at the gene level and pinpointing these differences can help guide targeted research and interventions. This study provides the first transcriptomic analysis of primary nasal airway epithelial cells in survivors of preterm birth at approximately 1 year of age.
Four outstanding researchers from the Wal-yan Centre - Professor André Schultz, Professor Stephen Stick, Rebecca Watson and Michael Beaven - have been presented with prestigious awards in acknowledgement of their research aimed at improving the lives of children with respiratory illness.
Lung function testing and lung imaging are commonly used techniques to monitor respiratory diseases, such as cystic fibrosis (CF). The nitrogen (N2) multiple-breath washout technique (MBW) has been shown to detect ventilation inhomogeneity in CF, but the underlying pathophysiological processes that are altered are often unclear.
This study found rhinovirus infection drives necrotic cell death in cystic fibrosis airway epithelial cells