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The main mission of the Australian and New Zealand Children's Haematology and Oncology Group is to develop and facilitate local access to the world's leading evidence-based clinical trials for all paediatric cancers, including brain tumours, as soon as practically possible.
Patient-derived orthotopic xenograft (PDOX) mouse models are considered the gold standard for evidence-based preclinical research in pediatric neuro-oncology. This protocol describes the generation of PDOX models by intracranial implantation of human pediatric brain cancer cells into immune-deficient mice, and their continued propagation to establish cohorts of animals for preclinical research.
The Zero Childhood Cancer Program is a precision medicine program to benefit children with poor-outcome, rare, relapsed or refractory cancer. Using tumor and germline whole genome sequencing (WGS) and RNA sequencing (RNAseq) across 252 tumors from high-risk pediatric patients with cancer, we identified 968 reportable molecular aberrations.
Recognising the signs of type 1 diabetes (T1D) can be tricky. Often put down to growing pains, a virus or “something going around”, a diagnosis can take some time if children aren’t severely sick and attend an emergency department.
Australia’s largest study into the causes of type 1 diabetes reached a significant milestone when it recruited its first family in Perth with three children recently.
Nearly six return trips to the moon — 4,612,800km — that’s the incredible distance Telethon Kid Institute’s Children’s Diabetes Centre (CDC) staff have collectively travelled to deliver specialist care to kids living with diabetes in regional Western Australia over the past 28 years.
Find out about many of our previous research studies and trials, and those that are ongoing but are no longer recruiting participants.
In this new blog, Senior Speech Pathologist Marisa Di Lorenzo discusses Augmentative and Alternative Communication and how it supports every individual’s access to the basic right of communication.
Determining if hyperglycaemia prior to and during exercise affects the amount of carbohydrate required to maintain stable glucose levels during/after exercise
We have all heard of the phrase ‘it takes a village to raise a child’ but unfortunately in contemporary western society that ‘village’ can be hard to find.