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Research

Impact of Childhood Pneumococcal Conjugate Vaccine on Nonnotified Clinically Suspected Invasive Pneumococcal Disease in Australia

This study provides a quantitative estimate of the total burden of invasive pneumococcal disease preventable by vaccination programs in Australia

Research

The pervasive effects of timing of parental mental health disorders on adolescent deliberate self-harm risk

This study shows that timing is important for understanding intergenerational transmission of deliberate self-harm risk

Research

Exposure to Solar UVR Suppresses Cell-Mediated Immunization Responses in Humans: The Australian Ultraviolet Radiation and Immunity Study

Higher UVR exposure at antigen sensitization was associated with a reduced delayed-type hypersensitivity response and altered T helper type 17 kinetics

Research

Overcrowded housing: One of a constellation of vulnerabilities for child sexual abuse

The findings suggest that overcrowded living conditions are associated with an increased risk of sexual abuse for some children

Research

Gamifying Breastfeeding for Fathers: Process Evaluation of the Milk Man Mobile App

The Milk Man app was an acceptable source of breastfeeding information and support that fathers and fathers-to-be are prepared to use throughout the perinatal period

Research

Acquired resistance during adoptive cell therapy by transcriptional silencing of immunogenic antigens

These findings suggest that tumor cells employ multiple epigenetic and genetic mechanisms to evade immune control

Research

MicroRNA Signatures in Malignant Pleural Mesothelioma Effusions

These results suggest that the expression of miR-143, miR-210, and miR-200c in PE cells might provide a signature for diagnosing malignant pleural mesothelioma

Research

Talking skin: Attitudes and practices around skin infections, treatment options, and their clinical management in a remote region in Western Australia

Documenting carer, service provider and healthcare practitioner perspectives on skin infections provides more understanding of the context of treatment decisions

Research

Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3

These findings implicate the activation of STAT3 as one pathway that may mediate resistance to IGF-II-targeted therapy in HCC

Research

Increased Use of Adrenaline in the Management of Childhood Anaphylaxis Over the Last Decade

There was a significant improvement in the management of anaphylaxis after the introduction of intensified physician training programs