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Research
Developing evidence-based recommendations for optimal interpregnancy intervals in high-income countries: Protocol for an international cohort studyWe aim to assess the impact of interpregnancy intervals on maternal and child health outcomes in high-income countries
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Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skinOur results show that TRM cells have a fundamental role in the surveillance of subclinical melanomas in the skin by maintaining cancer-immune equilibrium
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Intellectual disability and psychotic disorders in children: Association with maternal severe mental illness and exposure to obstetric complicationsMaternal severe mental illness and exposure to obstetric complications contribute separately to the risk of intellectual disability
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Vaccine acceptance: Science, policy, and practice in a ‘post-fact’ worldWe must continue our efforts to promote vaccine acceptance and thus increase vaccination uptake, by fostering more effective vaccination communication
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Age at menarche and childhood body mass index as predictors of cardio-metabolic risk in young adulthood: A prospective cohort studyEarlier age at menarche may be indicative of a higher risk profile for cardiovascular disease in young adulthood
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Are children more vulnerable to mesothelioma than adults?We found no greater susceptibility to mesothelioma among those first exposed to asbestos as children than those first exposed as adults
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Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 studyThe age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average
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Vitamin D is crucial for maternal care and offspring social behaviour in ratsThese data highlight that early life levels of vitamin D are an important consideration for maternal behavioural adaptations as well as offspring neuropsychiatry
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Effects of human rhinovirus on epithelial barrier integrity and function in children with asthmaThis study demonstrates novel intrinsic differences in tight junctions gene and protein expression between airway epithelial cells of children with and without asthma
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An investigation of the determinants of quality of life in adolescents and young adults with Down syndromeQuality of life of young people with Down syndrome was most negatively associated with burden of medical conditions, but also with lack of friendships