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The purpose of this randomized clinical trial is to determine whether the use of the BIB aids weight loss in obese adolescents.
Christopher Blyth MBBS (Hons) DCH FRACP FRCPA PhD Centre Head, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases
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Re: Recommendations from the Diabetes and Endocrinology Department at Perth Children’s Hospital and the Children’s Diabetes Centre at The Kids Research Institute Australia regarding COVID-19 vaccination for children with diabetes
Kids with diabetes should think beyond just carbs, according to The Kids Research Institute Australia senior dietitian Dr Amelia Harray.
Patients require on average about 50 per cent more insulin with a high protein meal than with a low protein meal. A study conducted by the Children's Diabetes Centre used an insulin clamp technique to determine insulin requirements to maintain euglycaemia across the different meals.
The Wesfarmers Centre is pleased to announce the 4 successful applications for the 2016 Round 1 Wesfarmers Centre Seed Funding.
Cancer cells are addicted to polyamines, polycations essential for cellular function. While dual targeting of cellular polyamine biosynthesis and polyamine uptake is under clinical investigation in solid cancers, preclinical and clinical studies into its potential in haematological malignancies are lacking. Here we investigated the preclinical efficacy of polyamine depletion in acute leukaemia.
It is now well accepted that germline or de novo genetic alterations predispose to cancer development, especially during childhood. Among them, constitutive trisomy 21, also known as Down syndrome (DS), has been shown to predispose to acute leukemia affecting both the myeloid (ML-DS) and lymphoid (DS-ALL) lineages. ML-DS is associated with a good prognosis compared to children without DS, due in part to a higher sensitivity to conventional chemotherapy.