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Parental occupational exposure to exhausts, solvents, glues and paints, and risk of childhood leukemia

It is unknown whether parental occupational exposure to chemicals before during and after pregnancy increases the risk of acute lymphoblastic...

Exposure to professional pest control treatments and the risk of childhood acute lymphoblastic leukemia

Previous studies suggest that exposure to pesticides increases the risk of childhood acute lymphoblastic leukemia

Integrated Analysis of miRNA and mRNA Expression in Childhood Medulloblastoma Compared with Neural Stem Cells

Medulloblastoma (MB) is the most common malignant brain tumor in children and a leading cause of cancer-related mortality and morbidity.

Late-talking and risk for behavioral and emotional problems during childhood and adolescence

Although many toddlers with expressive vocabulary delay ("late talkers") present with age-appropriate language skills by the time they are of school age,...

Prenatal maternal stress associated with ADHD and autistic traits in early childhood

Research suggests that offspring of mothers who experience high levels of stress during pregnancy are more likely to have problems in neurobehavioral...

Exposure to diagnostic radiological procedures and the risk of childhood acute lymphoblastic leukemia

Diagnostic irradiation of the mother during pregnancy increases the risk of childhood acute lymphoblastic leukemia

Vector fields of risk: A new approach to the geographical representation of childhood asthma

One of the major challenges in health studies with a spatial dimension is to produce valid and meaningful geographical representations of risk.

Few sex differences in regional gray matter volume growth trajectories across early childhood

Sex-specific developmental differences in brain structure have been documented in older children and adolescents, with females generally showing smaller overall brain volumes and earlier peak ages than males. However, sex differences in gray matter structural development in early childhood are less studied. We characterized sex-specific trajectories of gray matter volume development in children aged 2–8 years.  

A new direction for the MAP study: using proteins to help predict childhood asthma

The Metabolomics to Predict Asthma (MAP) study has reached an important turning point. After examining the ‘chemical fingerprints’ of more than 300 children, the team is now taking a new approach, turning to proteins to better understand which young children with recurrent wheeze go on to develop asthma.

Primary Nasal Epithelial Cells as a Surrogate Cell Culture Model for Type-II Alveolar Cells to Study ABCA-3 Deficiency

ATP Binding Cassette Subfamily A Member 3 (ABCA-3) is a lipid transporter protein highly expressed in type-II alveolar (AT-II) cells. Mutations in ABCA3 can result in severe respiratory disease in infants and children. To study ABCA-3 deficiency in vitro, primary AT-II cells would be the cell culture of choice although sample accessibility is limited. Our aim was to investigate the suitability of primary nasal epithelial cells, as a surrogate culture model for AT-II cells, to study ABCA-3 deficiency.