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Interaction between adaptive and innate immune pathways in the pathogenesis of atopic asthma: Operation of a lung/bone marrow axis

Atopic asthma is the most common form of asthma, particularly during childhood, and in many cases it persists into adult life.

Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study

Vitamin D has been linked in some studies with atopy- and asthma-associated phenotypes in children with established disease,but its role in disease inception...

Two newly identified cat allergens: The von Ebner gland protein Fel d 7 and the latherin-like protein Fel d 8

Characterization of the complete IgE binding spectrum of cat allergens is important for the development of improved diagnosis and effective immunotherapeutics.

Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study

The objective of this study was to compare international trends in pre-eclampsia rates and in overall pregnancy hypertension rates...

Molecular Epidemiology of Noninvasive and Invasive Group A Streptococcal Infections in Cape Town

There is low coverage of the multivalent M protein vaccine in our setting, emphasizing the need to reformulate the vaccine to improve coverage

Measurement of urinary 1-aminopyrene and 1-hydroxypyrene as biomarkers of exposure to diesel particulate matter in gold miners

The concentrations of 1-AP and 1-OHP increased significantly across a 12-hour mining work shift

Mental Health Correlates of Autism Spectrum Disorder in Gender Diverse Young People: Evidence from a Specialised Child and Adolescent Gender Clinic in Australia

Current findings indicate that gender diverse children and adolescents with indicated ASD comprise an especially vulnerable group at risk of mental health difficulties

Changing Prevalence of Lower Airway Infections in Young Children with Cystic Fibrosis

Aspergillus species and P. aeruginosa are commonly present in the lower airways from infancy

Understanding acute burn injury as a chronic disease

The review will outline evidence of long-term health effects, possible mechanisms linking burn injury to long-term health and current research into burns as a chronic disease

An update on allergy and anaphylaxis in pediatric anesthesia

We review the pathophysiology of hypersensitivity reactions and the implications for anesthesia of food allergy, atopy, and family history of allergy in children