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Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweightWe find that DNA methylation in neonatal blood is associated with birthweight, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation
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Effect of 6 months of hybrid closed-loop insulin delivery in adults with type 1 diabetes: A randomised controlled trial protocolDetermine the effectiveness of 6 months' closed-loop compared with manually determined insulin dosing on time-in-target glucose range in adults with type 1 diabetes
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Characteristics of Automated Insulin Suspension and Glucose Responses with the Predictive Low-Glucose Management SystemLonger suspends and fewer glycemic excursions occur at night compared with day
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The time lag prior to the rise in glucose requirements to maintain stable glycaemia during moderate exercise in a fasted insulinaemic state is of short durationThere is a 20-min low exogenous glucose demand period during which the glucose requirements to maintain stable glycaemia do not increase during moderate exercise
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ISPAD Clinical Practice Consensus Guidelines 2018: Exercise in children and adolescents with diabetesPromotion of regular physical activity is an integral part of diabetes care delivery and health care providers should promote this message at every available opportunity
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Analysis of glucose responses to automated insulin suspension with sensor-augmented pump therapyThe advent of sensor-augmented pump therapy with a low-glucose suspend (LGS) function.
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High incidence of obesity co-morbidities in young children: A cross-sectional studyThe prevalence of overweight and obesity in children is a public health problem because of future morbidity.
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Improving epinephrine responses in hypoglycemia unawareness with real-time continuous glucoseThe objective of this study was to determine whether real-time continuous glucose monitoring (CGM) with preset alarms at specific glucose levels would prove...
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Comprehensive genetic screening: The prevalence of maturity-onset diabetes of the young gene variants in a population-based childhood diabetes cohortThis is the first comprehensive study of maturity-onset diabetes of the young variants in an unselected population-based pediatric diabetes cohort
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The glycaemic benefits of a very-low-carbohydrate ketogenic diet in adults with Type 1 diabetes mellitus may be opposed by increased hypoglycaemia risk and dyslipidaemiaThis study provides the first evidence that, ketogenic diets in adults with Type 1 diabetes are associated with excellent HbA1c levels and little glycaemic variability