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Research

Successful establishment of primary small airway cell cultures in human lung transplantation

The study of small airway diseases such as post-transplant bronchiolitis obliterans syndrome (BOS) is hampered by the difficulty in assessing peripheral airway

Research

Adolescent dietary patterns are associated with lifestyle and family psychosocial factors

Few studies have examined the dietary patterns of adolescents and the social and environmental factors that may affect them during this life stage.

Research

The reliability of a food frequency questionnaire for use among adolescents

Accurate measurement of dietary intake is essential for understanding the long-term effects of adolescent diet on chronic disease risk.

Research

Effects of simulated tidal and deep breathing on immature airway contraction to acetylcholine and nerve stimulation

In adults, respiratory movements, such as tidal and deep breaths, reduce airway smooth muscle force and cause bronchodilation.

Research

Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells

Tumor cell death potentially engages with the immune system. However, the efficacy of anti-tumor chemotherapy may be limited by tumor-driven...

Research

Hemispheric division of function is the result of independent probabilistic biases

Causal theories propose that functional asymmetry is an obligatory pattern of organisation, while statistical theories maintain this is a reflection...

Research

Adult psychosocial outcomes of children with specific language impairment, pragmatic language impairment and autism

Evidence that some children also develop autistic symptomatology over time has raised suggestions that developmental language disorder...

Research

The common BDNF polymorphism may be a modifier of disease severity in Rett syndrome

Rett syndrome (RTT) is caused by mutations in the transcriptional repressor methyl CpG-binding protein 2 (MECP2).

Research

Impact of scoliosis surgery on activities of daily living in females with Rett syndrome

Scoliosis is a common orthopaedic complication of Rett syndrome, and surgery is commonly used to reduce asymmetry in cases with severe scoliosis.

Research

Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolism

We examined the baseline profile of a panel of T-ALL cell lines to determine factors that contribute to GC resistance without prior drug selection.